Gabapentine & Nortriptyline Hydrochloride Tablets (BEGO-NT)

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149  
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149
  • Primary Uses: It is primarily used to control certain types of partial seizures in individuals with epilepsy and to relieve the pain of postherpetic neuralgia (nerve pain after shingles). It is also used off-label for conditions like restless legs syndrome and fibromyalgia.
  • Mechanism of Action: It works by calming overactive nerves in the body. It binds to specific sites on nerve cells (voltage-gated calcium channels) to modulate their activity, which helps decrease the transmission of pain signals in the brain.
  • Key Consideration: The dose often needs adjustment for patients with kidney disease because it is primarily eliminated through the kidneys. 

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